Autologous Chondrocyte Transplantation / Implantation Versus Existing treatments


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Chondral defects
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ACTIVE PEOPLE

Chief Investigator

Professor James Richardson, Consultant in Orthopaedics, Keele University, Robert Jones & Agnes Hunt Orthopaedic Hospital.

Trial Manager

Dr Johanna Wales, Robert Jones & Agnes Hunt Orthopaedic Hospital.

Co-investigators

Professor Richard Gray, University of Birmingham Clinical Trials Unit.

Professor Marilyn James, Nottingham Univerisity.

Professor George Bentley, Royal National Orthopaedic Hospital, Stanmore.

Principal Investigators

ACTIVE surgeons

Trial Steering Committee

Professor Neil Rushton, Orthopaedic Research Unit, Cambridge.

Dr Martin Landray, Clinical Trials Service Unit, Oxford.

Professor James Richardson, Robert Jones & Agnes Hunt Orthopaedic Hospital.

Professor Richard Gray, University of Birmingham Clinical Trials Unit.

Professor George Bentley, Royal National Orthopaedic Hospital, Stanmore.

Professor Marilyn James, Nottingham Univerisity.

Data Monitoring and Ethics Committee

Professor Hamish Simpson, University of Edinburgh.

Dr Paresh Jobanputra, Department of Rheumatology, University of Birmingham.

Dr Emma Hall, Clinical Trials & Statistics Unit, Surrey.

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ACTIVE is being carried out by the Robert Jones & Agnes Hunt Orthopaedic & District Hospital NHS Trust in collaboration with the University of Birmingham Clinical Trials Unit and Health Economics Facility. The trial is funded by the Medical Research Council and administrated by Keele University.